Claims extracted
19
sentences that state something as happening or true
Uncertain
11%
2 of 19 hedged
("reportedly", "may", "according to")
Leaning
not political
takes no side on a contested political question
Publisher signals
67/100
ABC News (US)'s corrections and
hedging, across everything collected from it. Not a measure of accuracy.
Outlets on this story
2
Health
Same framing elsewhere
1
articles that frame the event the way this one does
FDA examines use of testosterone prescriptions for menopause
asserted
FDA → examine → menopause
There is rising off-label use of testosterone among menopausal women.
Testosterone therapy is increasingly being used by menopausal women but specialists at a Food and Drug Administration (FDA) public workshop cautioned on Thursday that key questions about its long-term safety remain unanswered.
asserted
questions → be → safety
Studies show that while adult males generally have 15 times more total testosterone than females, testosterone is the most abundant sex hormone in premenopausal women, produced at about three times the rate of estrogen.
asserted
testosterone → show → estrogen
With age, women's testosterone levels gradually decline, and low levels have been linked to loss of bone density and muscle mass, along with declines in cognition, mood, sexual function and energy.
asserted
levels → decline → cognition
Because there is no FDA-approved testosterone formulation for women in the U.S., clinicians who prescribe the hormone may do so off-label and use smaller doses of testosterone products designed for men.
uncertain
who → be → men
"There are no FDA-approved uses for testosterone therapy for menopausal women," Dr. Christina Chang, division director of the division of urology, obstetrics and gynecology in the FDA's Center for Drug Evaluation and Research said at the FDA workshop Thursday.
asserted
Chang → be → workshop
She noted that the agency is aware of increasing off-label use of testosterone among women experiencing menopause.
asserted
agency → note → menopause
Currently, evidence supporting testosterone therapy in women is largely focused on hypoactive sexual desire disorder, a condition characterized by persistently low sexual desire that causes distress.
asserted
that → support → distress
Specialists in the FDA workshop on Thursday said women are seeking testosterone for a much broader range of concerns including energy and mood.
asserted
women → say → energy
Based on current guidelines, testosterone therapy is not considered a treatment for these symptoms.
asserted
therapy → base → symptoms
Measuring testosterone in women also presents challenges because concentrations are much lower than in men.
asserted
concentrations → measure → men
As such, there is no blood-test threshold that can diagnose whether a woman has a testosterone deficiency.
asserted
woman → be → deficiency
Unlike estrogen, testosterone levels do not suddenly fall when women reach menopause.
asserted
women → fall → menopause
"There is a gradual decline in testosterone levels across the premenopausal levels," Dr. Margaret Wierman, professor of medicine at the University of Colorado School of Medicine, told ABC News.
asserted
Wierman → be → News
The growing interest in testosterone comes amid an increase in hormone replacement therapy (HRT) among menopausal women, which typically uses estrogen with or without progesterone to replace declining hormones during menopause.
asserted
which → grow → menopause
HRT prescriptions among women ages 50 to 65 rose 72% from 2021 to 2025, according to data from Epic Research.
uncertain
prescriptions → rise → Research
It comes after the FDA removed its "black box" warning label from HRT products for menopause earlier this year followed by the removal of the warning on testosterone products.
asserted
FDA → come → products
"Menopause is inevitable, women should not have to suffer through it," Chang said.
asserted
Chang → have → it
"To best serve the American women we need high-quality data and we are looking forward to working with all the manufacturers to be able to get that data."
asserted
we → serve → data
The Aporia
