Photo via The Globe and Mail

Novel ‘heart in a box’ technology gives London, Ont., patient ‘second life’

Read the original at The Globe and Mail ↗
Cite

Kirkup, K. (2026, September 24). Novel ‘heart in a box’ technology gives London, Ont., patient ‘second life’. The Globe and Mail. https://www.theglobeandmail.com/canada/article-novel-heart-in-a-box-technology-gives-london-ont-patient-second-life/

Dated when The Aporia collected the article, usually within hours of publication. Check the original for its exact date and byline.

The Globe and Mail · collected 2026-09-24 · by Kristy Kirkup

Quick Summary

Raj Mittal received a heart transplant using “heart in a box” technology at London Health Sciences Centre in February 2025, becoming the first Canadian patient to benefit from this innovative method. The device, known formally as an Organ Care System by TransMedics, keeps donor hearts warm and pumping blood for up to 12 hours, compared to four degrees Celsius storage that allows only six hours of viability. This technology not only extends the travel distance for transplanted hearts but also revives hearts after they have stopped beating, potentially expanding the pool of viable donors.
Written by AI on 2026-09-24, from this article's own text only (the story summary below draws on all the coverage).

AI analysis

Story summary

Raj Mittal, a resident of London, Ontario, received a groundbreaking heart transplant in February 2025 using "heart in a box" technology from the London Health Sciences Centre. This novel device, also known as an Organ Care System, allows hearts to remain viable for up to 12 hours after removal, significantly extending their travel distance compared to the previous six-hour limit when preserved on ice. Mittal's heart condition led him to a cardiac arrest and a triple bypass in June 2025, followed by a month-and-a-half stay in intensive care. After being added to Ontario’s transplant list, he received his new heart two weeks later. Dr. Nagpal explained that the device enables doctors to monitor the heart's function visually and through lab tests while it is still beating inside the machine. This advancement has given Mittal a "second life" and highlights a major improvement in organ transplantation technology in Canada.

Written for “Heart In A Box Technology” on 2026-11-01, grounded in this article and the 0 other(s) covering the same event.

Story

📰 Heart In A Box Technology
Health · 1 article(s) covering the same event.

Compared with similar articles

Nothing to compare against. No article is close enough to this one for the pipeline to have linked or judged the pair.
How this article was measured signals, leaning charts, publisher record, byline, topics and claims

Signals How these are calculated →

Claims extracted
42
sentences that state something as happening or true
Uncertain
7%
3 of 42 hedged ("reportedly", "may", "according to")
Leaning
not political
takes no side on a contested political question
Publisher signals
52/100
The Globe and Mail's corrections and hedging, across everything collected from it. Not a measure of accuracy.
Outlets on this story
1
Health
Same framing elsewhere
1
articles that frame the event the way this one does
Analyzed 2026-09-24 · how these are computed

How this is being covered How these are calculated →

Article leaning vs. publisher reliability
Source leaning vs. consistency

Publisher

The Globe and Mail · 1030 article(s) · 35 correction(s) detected
Running correction rate · 35 correction(s)

Who wrote this

Kristy Kirkup
16 article(s) here · 1 carrying a prediction
🔮 Dr. Jerath said a possible explanation for the differences could be that female physicians may engage in more patient-centred communication and that they spend more time with their patients.
🔮 So depending on where the attack occurs, you could have a multitude of different symptoms, or you could have no symptoms at all.
🔮 By the end of a two-day interjurisdictional meeting, Canada’s provincial and territorial health ministers were able to receive assurances on funding extensions from Ottawa, but will need to convene again before 2027 to confirm the future of expiring transfer programs.
🔮 Canada’s provincial and territorial health ministers say Ottawa’s one-year extension of funding for mental health, addiction treatment and home care is not enough, and that federal plans would amount to a spending cut that is “the largest in a generation.”
🔮 The model could serve as an example for other centres across the country as Canada experiences rapid growth in its aging population.
🔮 An Ontario father of two with Stage 4 melanoma says he is heartbroken that the provincial government’s revised rules for out-of-country medical coverage will continue to bar access to a treatment that could save his and others’ lives.
🔮 At the time, a nurse told her any other surgeon would have done a hysterectomy because her situation was “a mess.”
🔮 U.S. President Donald Trump signalled that he supports the idea, but his energy secretary recently indicated a “blanket ban” will not happen.
2026-09-28 · assertive framing · Poilievre pushes for diesel plan as fuel prices soar
🔮 After a cardiac arrest and a triple bypass in June, 2025, he spent a month and a half sedated in intensive care at the London Health Sciences Centre in Ontario before he could return home to his wife and two children.
🔮 “The record discloses that he will likely be dead by Christmas if he does not receive the requested treatment within a few weeks,” the justices said.
Also by Kristy Kirkup
Nothing else under this byline is closely related to this article, so these are simply their most recent.
All 16 articles by Kristy Kirkup →

Topics

Canadian London Ontario an Organ Care System the London Health Sciences Centre

Subjects

Mittal PERSON · 7× Ontario GPE · 3× Canadian NORP · 2× London GPE · 2× Nagpal PERSON · 2× Nedadur PERSON · 2× the London Health Sciences Centre ORG · 2× Dave Nagpal PERSON · 1× Raj Mittal’s PERSON · 1× TransMedics ORG · 1×

Narrative

“You can hook the heart up to this device and actually watch it regain function and assess the function of the heart based on the visual appearance, but also based on the laboratory investigations that we can do on the device,” Dr. Nagpal said.
framing: assertive · carried by 1 article(s) · first seen 2026-09-24
🔮 After a cardiac arrest and a triple bypass in June, 2025, he spent a month and a half sedated in intensive care at the London Health Sciences Centre in Ontario before he could return home to his wife and two children.
2026-09-24 · The Globe and Mail
Novel ‘heart in a box’ technology gives London, Ont., patient ‘second life’ · assertive framing

Claims (42 extracted, 3 hedged)

Raj Mittal’s new heart came in an unusual package. asserted
heart → come → package
After a cardiac arrest and a triple bypass in June, 2025, he spent a month and a half sedated in intensive care at the London Health Sciences Centre in Ontario before he could return home to his wife and two children. uncertain
he → spend → wife
When his heart condition led to pneumonia in January and another hospital stay, he learned he was a candidate for a heart transplant. asserted
he → lead → transplant
Typically heart donors are patients who have been declared brain dead, but whose hearts are still beating. asserted
hearts → declare → ?
Once the organs are removed they are placed on ice, and can last in this state for only up to six hours, limiting how far they can travel. asserted
they → remove → hours
But when Mr. Mittal’s heart arrived in February, two weeks after he was added to Ontario’s transplant list, it was still warm and pumping blood. asserted
it → arrive → blood
According to the London hospital, which performed the transplant, he was the first Canadian to receive what is is colloquially called a “heart in a box.” uncertain
what → accord → box
The box, which is actually a cart-sized medical device on wheels with a chamber where the organ can rest and receive blood through a system of tubes, doubles a donor heart’s potential lifespan to 12 hours. asserted
organ → rest → hours
With the longer timeframe, a heart can travel much farther than was previously possible. asserted
heart → travel → timeframe
The box can also revive hearts after they stop beating, expanding the pool of donors to include patients who die after circulation stops. asserted
circulation → revive → patients
In ordinary circumstances, these organs wouldn’t be considered viable. asserted
organs → consider → circumstances
“It’s a second life for me,” said Mr. Mittal, a 50-year-old information technology professional. asserted
Mittal → ’ → me
Dave Nagpal, medical co-director of the multiorgan transplant program at the London Health Sciences Centre and its director of cardiac transplantation, called the technology “fascinating.” asserted
Nagpal → call → technology
The box, formally known as an Organ Care System, is made by TransMedics, a company headquartered in Massachusetts. asserted
box → know → Massachusetts
Once a donor heart is removed, Dr. Nagpal said, the device can be attached to the organ, which starts pumping again. asserted
which → remove → organ
“You can hook the heart up to this device and actually watch it regain function and assess the function of the heart based on the visual appearance, but also based on the laboratory investigations that we can do on the device,” Dr. Nagpal said. asserted
Nagpal → hook → device
“This additional technology allows us to get more donor hearts into those recipients that really need them.” asserted
that → allow → them
He acknowledges it took a village for the technology to be made available in Ontario. asserted
technology → acknowledge → Ontario
Hearts from Canadian donors have previously been revived in the devices, but they were transplanted into American recipients. asserted
they → revive → recipients
Ontario Health, a provincial agency, financed the equipment. asserted
Health → finance → equipment
The acquisition took years of collaboration with the Trillium Gift of Life Network, an agency responsible for delivering and co-ordinating organ and tissue donation and transplantation services across the province. asserted
acquisition → take → province
And the physicians who would use the device required special training. asserted
who → use → training
Before Mr. Mittal’s transplant, the hospital’s cardiac surgeon, Rashmi Nedadur, had to retrieve the donor’s heart from another location that the hospital says it cannot disclose. asserted
it → have → that
Dr. Nedadur assessed how the heart was functioning and deemed it viable for transplant. asserted
it → assess → transplant
He brought it back to the London hospital, where a surgical team was prepped and ready to scrub in. asserted
team → bring → hospital
In the operating room, major vessels were trimmed to fit Mr. Mittal’s anatomy. asserted
vessels → trim → anatomy
The heart also needed to be protected through a process that involved special solutions and temperature control. asserted
that → need → solutions
Once the heart was sewn into Mr. Mittal’s chest, Dr. Nedadur said, the heart “took off immediately.” asserted
heart → sew → chest
Just days after the transplant procedure Mr. Mittal started feeling more like himself. asserted
Mittal → start → himself
He could get up and move in the intensive care unit, before he was transferred to the hospital’s transplant unit. uncertain
he → get → unit
He had to return briefly to the ICU to manage his blood pressure and fluid levels. asserted
He → have → pressure
But later that month he was able to go home. asserted
he → go → ?
These days, Mr. Mittal is recovering well. asserted
Mittal → recover → ?
But he said he has to remind himself to go slow. asserted
he → say → himself
He is doing cardiac rehabilitation and takes medication daily. asserted
He → do → medication
Although he remains on leave from his job, he is finding joy in simple things, such as being able to get outside for walks. asserted
he → remain → walks
This is a marked improvement from life before the transplant, he said, when his energy levels were so low he couldn’t enjoy time with family. asserted
he → say → family
He hopes that with more time, his new heart will eventually allow him to get back to doing more. asserted
him → hop → more
His main goals are to return to work, and, by next summer, get back on his bike. asserted
goals → return → bike
He enjoys riding alongside his children, now 11 and 17. asserted
He → rid → children
…and 2 more, not listed.
💬Give feedback
🕘History 🎫Support