Human Brain Cells In Mice

What happened

The outlets' own sentences, most widely reported first. Hover or tap one to see who reported it.

Analysis

How it changed

1. 16 Sep

   Researchers have developed a new way to install millions of human brain cells into mice, as a way of creating better scientific models for studying neurodegenerative disease.

   3 outlets · NPR
2. 18 Sep

   Images included in the report showed how the mice, which were bred with part of their cerebrum missing, had a full brain after the cortical organoid transplant.

   2 outlets · New York Post

Coverage 5 articles

• 19 Sep Stanford scientists grow human brain tissue inside mice, filling more than 90% of missing cortex spaceStanford researchers have successfully transplanted lab-grown human brain tissue into mice engineered to lack most of their cerebral cortex. Within months, this tissue expanded to fill over 90% of the available space in these modified mice, forming functional connections with the mouse’s nervous system. Published in Nature on September 16, the study uses cortical organoids derived from human stem cells to observe…Times of India
• 19 Sep Neuroscientist explains how his team grew human brain tissue in mice and breaks down what they foundDr. Sergiu Pasca from Stanford University discusses his team's research where they grew human brain tissue inside mice. This experiment aims to advance treatments for various brain disorders. On CBS News, Dr. Pasca explains the methodology and results of their study.CBS News
• 18 Sep Stanford geniuses create lab rats with half-human brainsScientists at Stanford University have successfully transplanted lab-grown human cortical organoids into mice, which had been bred with most of their cerebral cortex missing. Published in Nature, this study involves transforming human skin cells into stem cells that form brain tissue resembling the cerebral cortex. The transplanted tissue not only survived but also integrated with and developed connections to the…New York Post
• 16 Sep Part-human part-mouse brain developed in science breakthroughUS neuroscientists have created mice with functioning human cells in their brains to study psychiatric and neurodevelopmental diseases that cannot be effectively modeled in animals. The researchers genetically engineered the mice so they develop almost no cerebral cortex, then implanted brain-like tissue grown from human skin cells into these rodents. Published in Nature, this breakthrough aims to improve…BBC
• 16 Sep Mice with human brain cells offer a tool to study disease. Ethicists ask: What's next?Researchers have developed a method to implant millions of human brain cells into mice that lack parts of their cerebral cortexes. This technique allows scientists to study neurodegenerative diseases using more accurate models of the human brain than previously possible. The research, led by Sergiu Pașca from Stanford University and published in Nature, addresses ethical concerns while advancing scientific…NPR

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